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Effects of hypoxia on βAR expression: qPCR expression analysis reveals a significant increase in the number of βARs for both β1 and β2 adrenergic receptors in the 15 day embryos, where there is a 10-fold difference in their expression in the hypoxic-treated relative to the normoxic-treated samples. This vast increase in βARs in the hypoxic samples is not seen in the 19 day embryos.

Effects of age on hypoxic βAR expression: When comparing age there is a significant difference in the normalized relative β12 adrenergic receptor ratio seen in the hypoxic samples. The relative β12 expression increases in 15H but decreases in 19H, compared to the normoxic samples for each age.


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Last updated: 05/17/10