Results
Effects of hypoxia on βAR expression: qPCR expression analysis reveals a significant increase in the number of βARs for both β1 and β2 adrenergic receptors in the 15 day embryos, where there is a 10-fold difference in their expression in the hypoxic-treated relative to the normoxic-treated samples. This vast increase in βARs in the hypoxic samples is not seen in the 19 day embryos.
Effects of age on hypoxic βAR expression: When comparing age there is a significant difference in the normalized relative β1:β2 adrenergic receptor ratio seen in the hypoxic samples. The relative β1:β2 expression increases in 15H but decreases in 19H, compared to the normoxic samples for each age.
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Last updated:
05/17/10