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Conclusion

Chicken hypoxic hearts have increased heart mass/fetal mass ratio. Some of the identified genes are linked to cell division and others have no known function. They all merit further study for potential involvement in cardiac remodelling. With the little information available and although the qPCR did not confirm the microarray results, links between those genes and cell division have been made. This is considered to be a first step, more work should be put on them especially on the similar to ENS-1 gene which is of some importance since it is expressed in undifferentiated embryonic stem cells but is down regulated in induced embryonic stem cell.


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Last updated: 05/20/09