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Main Findings

Hypoxia increased Gαi, but not Gαs in the embryo.

Fig. 1 Mean values of Gαs and Gαi in the embryonic heart.

No significant difference was found in the levels Gαs between the hypoxic and the normoxic group (Fig. 1). The level of Gαi on the other hand, was significantly higher (22.3 %) in the hypoxic group than in the normoxic group, 115 % and 94 % of the internal standard respectively (Fig. 1)

Hypoxia increased Gαs, but not Gαi in the juveniles.

Fig. 2 Mean values of Gαs and Gαi in the juvenile heart.

In contrast to the embryos, hypoxia significantly increased Gαs in the juveniles by 21.5 % compared to the normoxic control (Fig. 2), though no significant difference in Gαi levels was found between the hypoxic and normoxic groups (Fig. 2).


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Last updated: 05/19/10