Thanks to Linkoping University, Sweden giving me the opportunity to perform this laboratory training at University of Copenhagen. I also acknowledge Department of Biomedical sciences, University of Copenhagen to host me in this project. I am really grateful to associate professor Carl-Henrik Brogren for his excellent supervision and very important support since my arrival in Copenhagen. Thanks to my home supervisor Dr Jordi Altimiras for his important instructions on my thesis. Also our technicians Susanne N Sorensen and Havva Koc have to get my warmest thanks for their introduction to the cell biology laboratory work and helpful advices. Besides, I also thanks to Amarnadh Nalla (Phd student), Manoj Desai (Master’s student), Md. Sayem Mia (Master’s student), and Md. Zoheb (Master’s student) to give me technical support and helpful advices during my laboratory work and also in writing thesis. Last but not least, I thank Institute director Niels Henrik Holstein-Rothlou for accept my stay and work in the Panum Institute.